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Dr. Harith Rajagopalan

Co-Founder & CEO, Fractyl Laboratories

Dr. Harith Rajagopalan is Co-Founder and CEO of Fractyl Laboratories. He is a cardiologist and medical device entrepreneur. He has worked with General Catalyst since 2009 as an XIR. He has also served as a medical consultant to a GC portfolio company, Corvia Medical, where he advises the company in its preclinical research and development activities.

Harith received his B.S. in Chemistry from Stanford University, where he gained a passion for both biomedical research and entrepreneurship. He went on to obtain MD and PhD degrees from Johns Hopkins School of Medicine. Harith won the Michael A. Shanoff award for his findings in colorectal cancer genetics and published this work in top medical journals, such as Nature and Science. After medical school, Harith did internal medicine residency training and cardiology fellowship at Brigham and Women’s Hospital and Harvard Medical School. He then completed a post-doctoral fellowship in stem cell biology before joining Fractyl as CEO.

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Jay Caplan

Co-Founder & President, Fractyl Laboratories

Jay holds a B.S. from the Massachusetts Institute of Technology and an MBA from The Wharton School.

Jay Caplan is Co-Founder and President of Fractyl Laboratories. Jay has held leadership positions in the medical device field for twenty years. Most recently Jay was the Chief Operating Officer of the Candela Corporation, the world leader in aesthetic devices.  From 2001 to 2007, he was Chief Technology Officer and Vice President Research and Development of InfraReDx, Inc. a venture-backed startup developing a novel cardiovascular imaging system to identify lipid-rich coronary plaques.  From 1999 to 2001, Jay was VP Operations for Thermo Cardiosystems, where he led the team developing the HeartMate II left ventricular assist device.

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General Catalyst Team

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