We are early in an AI transformation that will touch every industry, institution, and life. Dario Amodei and team are building Anthropic with the ambition and seriousness this moment demands.

In 2024, we made the unprecedented decision to acquire a hospital system and build a blueprint for proactive, accessible, affordable American healthcare. Now Summa Health and our Health Assurance Transformation Company (HATCo) have revealed their technology transformation stack, built with our portfolio companies Aidoc, Clarium, Commure, Fabric, Hippocratic AI, Judi Health, Transcarent, and Verse Medical, and unified by Percepta into a seamless AI-native operating system.

Hemant Taneja joins Packy McCormick for a candid Q2 review. Summa is becoming an AI-native hospital system, Janus is rebuilding the wealth experience, and both run on Percepta. Underneath it all sits one question about who the future of intelligence belongs to.

His second quarterly review builds the case around AI's concentration problem: the risk that the future of intelligence belongs to only seven companies. GC's counter-move is to drive the cost of intelligence down until it reaches founders at the edges and people on Main Street, handing agency back to them.

This is the context for Space: An Opening, our series on the future of commercial and sovereign space. We will examine the practical questions: the bottlenecks, business models and infrastructure layers that founders are working to resolve. But we wanted to begin somewhere more fundamental.

General Catalyst's Alexa Liautaud sits down with Castelion founder Bryon Hargis to discuss why solving cost and scale is the key to keeping America safe, how lessons from SpaceX are reshaping defense manufacturing, and why the cost of hypersonic missiles is breaking American deterrence.

Helsing is one of the most consequential AI companies in Europe, bringing AI-native software to defense systems. These capabilities strengthen Europe’s deterrence and enable its democratic institutions to flourish. We’re proud to deepen our partnership with Gundbert, Torsten, Niklas, and the entire team.