We are early in an AI transformation that will touch every industry, institution, and life. Dario Amodei and team are building Anthropic with the ambition and seriousness this moment demands.

In 2024, we made the unprecedented decision to acquire a hospital system and build a blueprint for proactive, accessible, affordable American healthcare. Now Summa Health and our Health Assurance Transformation Company (HATCo) have revealed their technology transformation stack, built with our portfolio companies Aidoc, Clarium, Commure, Fabric, Hippocratic AI, Judi Health, Transcarent, and Verse Medical, and unified by Percepta into a seamless AI-native operating system.

Scott Wu joins Hemant Taneja to talk about “tight-aggressive” leadership, first-generation entrepreneurship, the prisoner’s dilemma at the heart of the AI race, why safety is a real-world problem, and why no country can afford to be five years late on AI.

HT’s third quarterly review frames AI’s greatest risk as a prisoner’s dilemma built on low trust, where every nation, lab, and hyperscaler keeps racing because no one can afford to fall behind. The reward for working toward the future together, Hemant argues, is an AI economy that is resilient and sovereign.

This is the context for our short film, which began with a single line: "I want to ride my bike on the moon." The creative case for space takes many forms, from Carlo Rovelli's childhood dream of flying through the stars to Kubrick's 2001, made with Sagan and NASA and now strikingly prescient. Imagination precedes ambition, but only if someone funds the gap in between.

General Catalyst's Alexa Liautaud sits down with Castelion founder Bryon Hargis to discuss why solving cost and scale is the key to keeping America safe, how lessons from SpaceX are reshaping defense manufacturing, and why the cost of hypersonic missiles is breaking American deterrence.

Helsing is one of the most consequential AI companies in Europe, bringing AI-native software to defense systems. These capabilities strengthen Europe’s deterrence and enable its democratic institutions to flourish. We’re proud to deepen our partnership with Gundbert, Torsten, Niklas, and the entire team.